Research

KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway

KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice

A neuropathy-associated kinesin KIF1A mutation hyper-stabilizes the motor-neck interaction during the ATPase cycle

Betaine ameliorates schizophrenic traits by functionally compensating for KIF3-based CRMP2 transport

An activity-dependent local transport regulation via degradation and synthesis of KIF17 underlying cognitive flexibility

Kinesin Kif3b mutation reduces NMDAR subunit NR2A trafficking and causes schizophrenia-like phenotypes in mice

Hirokawa lab